Objections and requests for hearings must be received on or before January 4, 2021, and must be filed in accordance with the instructions provided in 40 CFR part 178 (see also Unit I.C. In estimating acute dietary exposure, EPA used food consumption information from the U.S. Department of Agriculture (USDA) 1994-1996 and 1998 Nationwide Continuing Surveys of Food Intake by Individuals (CSFII). Adequate enforcement methodology (Method GRM020.01A), which utilizes high performance liquid chromatography with triple-quadrupole mass spectrometry (LC-MS/MS) is available to enforce the tolerance expression. Objections and requests for hearings must be received on or before May 1, 2012, and must be filed in accordance with the instructions provided in 40 CFR part 178 (see also Unit I.C. ), nor does it require any special considerations under Executive Order 12898, entitled Federal Actions to Address Environmental Justice in Minority Populations and Low-Income Populations (59 FR 7629, February 16, 1994). Do NOT wash away into sewer. Box 18300, Greensboro, NC 27419. Because these products primarily affect cell elongation and not division, the number of new cells is only slightly reduced while their ability to elongate is significantly altered. Pesticide manufacturing (NAICS code 32532). We rated plots for lodging at harvest using a 1 10 scale with 0 equaling no lodging and 10 equaling complete lodging. EPA is setting different levels than were proposed based on EPA's analysis of the field trial data using the Organization for Economic Cooperation and Development tolerance calculation procedures. It is not an official legal edition of the Federal Lodging at head emergence, for example, can cause as little as 30 or as much as 80% yield reduction. documents in the last year, 522 The USGA promotes and conserves the true spirit of the game of golf as embodied in its ancient and honorable traditions. 2. [1]. of the SUPPLEMENTARY INFORMATION). To summarize this first year of work with plant growth regulators, we found a trend for one to two inch reductions in plant height when Palisade or Palisade plus Tilt were applied, but this only translated to increased grain yield at one site. While application of Palisade resulted in numeric reductions in plant height at Chickasha and Stillwater, differences among treatments were not statistically significant. Document page views are updated periodically throughout the day and are cumulative counts for this document. They were not associated with other neuropathological findings or overt neurological signs so their biological significance is unknown. error_outlineEmergency Number01484 538 444. As to residue levels in food, EPA assumed that residues are present in all commodities at the tolerance level and that 100% of commodities with tolerances are treated with trinexapac-ethyl. and services, go to This table of contents is a navigational tool, processed from the Avoid contact with skin and eyes. [Reserved], (d) Indirect or inadvertent residues. Lose the iron and calcium. The chemical structure of trinexapac-ethyl, including the . Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. EPA determines whether acute and chronic dietary pesticide exposures are safe by comparing aggregate exposure estimates to the aPAD and cPAD. Register (ACFR) issues a regulation granting it official legal status. documents in the last year, 861 Do not let the chemical enter drains. Agricultural Chemical. In addition, this action does not impose any enforceable duty or contain any unfunded mandate as described under Title II of the Unfunded Mandates Reform Act (UMRA) (2 U.S.C. The trinexapac-ethyl changes the size of the corn p lants, enabling new spatial arrangements. Discharge into the environment must be avoided. My Account; My Wishlist; My Cart; Checkout; Log In . This final rule is not a major rule as defined by 5 U.S.C. Only official editions of the The Agency understands the commenter's concerns and recognizes that some individuals believe that pesticides should be banned completely. EPA may establish a tolerance that is different from a Codex MRL; however, FFDCA section 408(b)(4) requires that EPA explain the reasons for departing from the Codex level. X. . daily Federal Register on FederalRegister.gov will remain an unofficial Garbacik, Chun-hui Ma, and C.W. Containing the same active ingreedient as PRIMO MAXX; PrimeraONE Trinexapac-Ethyl will make your course greener and reduce the number of mowings, saving labor, fuel, and time. Trinexapac-ethyl Rate the pronunciation difficulty of Trinexapac-ethyl 3 /5 (5 votes) Very easy Easy Moderate Difficult Very difficult Pronunciation of Trinexapac-ethyl with 1 audio pronunciations 0 rating Record the pronunciation of this word in your own voice and play it to listen to how you have pronounced it. that agencies use to create their documents. Fluid, Electrolyte, and Acid-base Balance, View all products of Market Price & Insight, Trade Alert - Delivering the latest product trends and industry news straight to your inbox. The OFR/GPO partnership is committed to presenting accurate and reliable This feature is not available for this document. Each document posted on the site includes a link to the documents in the last year, 37 Trinexapac-ethyl Chemical Structures GB RN 1422 Trade Name GOVERNOR G Label Indication Conventional Chemical CB RN 748461 Country USA Company THE ANDERSONS, INC. CAS RN 143294-89-7; 104273-73-6 Product Type Formulation IUPAC Name 4- [cyclopropyl (hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylic acid Compound Indication PLANT GROWTH REGULATOR Trinexapac-ethyl 11.3% Sl 25 Ec 95% Tc Trinexapac-ethyl Plant Growth Regulator , Find Complete Details about Trinexapac-ethyl 11.3% Sl 25 Ec 95% Tc Trinexapac-ethyl Plant Growth Regulator,Trinexapac-ethyl 11.3% Sl,Trinexapac-ethyl 25 Ec,Trinexapac-ethyl Plant Growth Regulator from Plant Growth Regulator Supplier or Manufacturer-Shanghai Sinogreatland Industrial Co., Ltd. What are the uses of Trinexapac-ethyl ? Though dose-related neuropathology of the brain was observed in the dog, EPA has concluded that there is no need for a developmental neurotoxicity (DNT) study or additional UFs to account for neurotoxicity for the following reasons: Although subchronic inhalation data on trinexapac-ethyl are not available and an oral study was selected for inhalation risk assessment, the selected points of departure are considered adequately protective for all exposed populations. For linear cancer risks, EPA calculates the lifetime probability of acquiring cancer given the estimated aggregate exposure. C. How can I file an objection or hearing request? Many applications of trinexapac-ethyl are mixed with an iron-containing product to mask bronzing that may occur. Application of Palidsade or Palisade plus Tilt resulted in numeric reductions in lodging scores at Stillwater in 2013, but the result were too variable to result in statistical significance. The documents posted on this site are XML renditions of published Federal The addition of iron and calcium does not render trinexapac-ethyl inactive, but it may decrease the activity at a given rate. While application of Palisade resulted in numeric reductions in plant height at Chickasha and Stillwater in 2013, differences among treatments were not statistically significant. The extract was directly injected into the HPLC system. . You may be potentially affected by this action if you are an agricultural producer, food manufacturer, or pesticide manufacturer. Our results are consistent with other wheat plant growth regulator research, which has reported similar variation in response among sites and years. Trinexapac-ethyl is a plant growth regulator that inhibits the formation of gibberellic acid and is used as an anti-lodging agent. In 2013 and 2014 we evaluated the plant growth regulator trinexapac-ethyl, which is sold under the trade name Palisade. on Open for Comment, Economic Sanctions & Foreign Assets Control, Electric Vehicle Standards and Requirements, Further Advancing Racial Equity and Support for Underserved Communities Through the Federal Government, Addendum to the Human Health Risk Assessment for Trinexapac-ethyl, Revised Residue Chemistry Chapter for Triexapac-ethyl. The acute toxicity of trinexapac-ethyl is low via the oral, eye, dermal, or inhalation routes of exposure, and it is not a dermal sensitizer. Short- and intermediate-term risk. Slowing flushes of warm-season turf growth with applications of trinexapac-ethyl i.e., Primo MAXX or post-patent products is an important part of reducing mowing inputs and other labor costs. This chemical is managed as part of a group or group(s). Registration Review. 4- (cyclopropylhydroxymethylene)-3,5-dioxocyclohexanecarboxylic Acid Ethyl Ester. . Many Oklahoma wheat farmers battled lodged wheat in 2013 and are looking to plant growth regulators to help reduce lodging in 2014. Box 18300, Greensboro, NC 27419. The Public Inspection page The experiment was arranged in a randomized block design in a factorial scheme, with three replications. Results of the acute neurotoxicity study show no indications of neurotoxicy at the highest dose. The President of the United States manages the operations of the Executive branch of Government through Executive orders. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. electronic version on GPOs govinfo.gov. has no substantive legal effect. Inquiry Basket () February,13th,2023; Hebei Luantong trade.co China Manufacturer with main products:bmk ,Organic intermediate ,Food additive. Wheat plant heightas affected by plant growth regulators in 2013, Wheat plant height as affected by plant growth regulator in 2014. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations. Acting Director, Registration Division, Office of Pesticide Programs. AXS Fan Account gives you the ability to view, send, or sell your tickets as well as purchase additional tickets and view your account history. Counts are subject to sampling, reprocessing and revision (up or down) throughout the day. 1.1 Name Trinexapac-ethyl 1.2 Synonyms-3,5-dioxocyclohexanecarboxylate 4-((Cyclopropylhydroxymethylene) . headings within the legal text of Federal Register documents. The United States is not able to harmonize its sugarcane tolerance with the Codex MRL; based on the reduction of the preharvest interval (PHI) from 28 to 14 days on sugarcane, the field trial data indicate that use in accordance with the label results in residues may exceed tolerances if they were harmonized with Codex. Provision to contain effluent from fire extinguishing. 02/28/2023, 239 documents in the last year, 983 This action directly regulates growers, food processors, food handlers, and food retailers, not States or Tribes, nor does this action alter the relationships or distribution of power and responsibilities established by Congress in the preemption provisions of FFDCA section 408(n)(4). In applying this provision, EPA either retains the default value of 10X, or uses a different additional safety factor when reliable data available to EPA support the choice of a different factor. documents in the last year, 20 Other names: Trinexapac-ethyl, trimethylsilyl ether Permanent link for this species. For non-threshold risks, the Agency assumes that any amount of exposure will lead to some degree of risk. These 180-degree nozzles can be used without the need to raise and lower booms, which makes applications easier where maneuverability is limited. The thicker the wheat crop and/or the taller the wheat crop, the more force that winds exert on the root anchorage system and the greater the likelihood of lodging. Cancer. The numbers in the figure do not account for harvest losses, which can exceed losses associated with lower photosynthetic capacity shown in the figure. Document page views are updated periodically throughout the day and are cumulative counts for this document. Pesticide Review Status. This MRL is different than the tolerances established for trinexapac-ethyl in the United States. It is interesting to note that the Palisade treatment increased grain yield at Perkins even though the plots lodged at comparable levels as the non treated check. The finer the spray particle size, the more uptake and suppression youre likely to get. documents in the last year, by the Federal Communications Commission You must file your objection or request a hearing on this regulation in accordance with the instructions provided in 40 CFR part 178. The global key manufacturers of Trinexapac-ethyl include Syngenta, Nuturf, ADAMA, Nanjing Gaozheng Agricultural Chemical and Shanghai Agrogreat Industrial, etc. Wheat lodging is not generally a widespread problem in Oklahoma, but it does occur. documents in the last year. Incidental oral (short and intermediate-term), No appropriate endpoint for the incidental oral scenario for children, Dermal & Inhalation (short- and intermediate-term-adults only), Dermal (or oral) study NOAEL = 60 mg/kg/day (dermal absorption rate = 77.5%. 3501 et seq. Two comments were received in response to the Notice of Filing. trinexapac-ethyl is approved for use . Soil metabolism of trinexapac-ethyl yields the major metabolite trinexapac, mineralisation to CO. 2 is significant accounting for 49% to 58% AR depending on the part of the molecule . Keep the chemical in suitable and closed containers for disposal. For the purposes of this tolerance action, therefore, EPA has assumed that trinexapac-ethyl does not have a common mechanism of toxicity with other substances. headings within the legal text of Federal Register documents. Last updated on July 5, 2022 Wheat grain yield as affected by plant growth regulator in 2013, Wheat grain yield as affected by plant growth regulator in 2014. 21 U.S.C. Compliance with the tolerance levels specified below is to be determined by measuring both trinexapac-ethyl, ethyl 4-(cyclopropylhydroxymethylene)-3,5-dioxocyclohexanecarboxylate and the associated metabolite, trinexpac, 4-(cyclopropylhydroxymethylene)-3,5-dioxocyclohexanecarboxylic acid, calculated as the stoichiometric equivalent of trinexapac-ethyl, in or on the commodity. Acute exposure. Section 408(b)(2)(C) of FFDCA provides that EPA shall apply an additional tenfold (10X) margin of safety for infants and children in the case of threshold effects to account for prenatal and postnatal toxicity and the completeness of the database on toxicity and exposure unless EPA determines based on reliable data that a different margin of safety will be safe for infants and children. Revising the existing entries in the table for Sugarcane, cane and Sugarcane, molasses. The Office of Management and Budget (OMB) has exempted these types of actions from review under Executive Order 12866, entitled Regulatory Planning and Review (58 FR 51735, October 4, 1993). Application of Palisade or Palisade plus Tilt increased grain yield at Perkins in 2014 even though there was no lodging. The telephone number for the Public Reading Room is (202) 566-1744, and the telephone number for the OPP Docket is (703) 305-5805. documents in the last year, 121 When following these steps, you will likely find higher than usual suppression, so lower application rates of actual product should be used. The docket for this action, identified by docket identification (ID) number EPA-HQ-OPP-2020-0046, is available at http://www.regulations.gov or at the Office of Pesticide Programs Regulatory Public Docket (OPP Docket) in the Environmental Protection Agency Docket Center (EPA/DC), West William Jefferson Clinton Bldg., Rm. documents in the last year, 522 In 2013 we evaluated the plant growth regulator trinexapac-ethyl, which is sold under the trade name Palisade. Important Announcement. ICP16009155-1 | Copyright@Qingdao ECHEMI Digital Technology Co., Ltd. Arginyl-arginyl-prolyl-tyrosyl-isoleucyl-leucine, Potassium 4-trifluoroboratomethylthiomorpholine, Spiro[isochroman-1,4'-piperidin]-3-one hydrochloride, 1,9-Bis[2-[ethyl[4-[2-(4-nitrophenyl)diazenyl]phenyl]amino]ethyl] nonanedioate, 2H-Tetrazolium, 2,3-bis(4-ethylphenyl)-5-phenyl-, chloride (1:1), high purity hot sale Trinexapac-ethyl 99% high quality see COA KANBEI, high purity hot sale Trinexapac-ethyl 99% high quality see COA KANBEI, ECHEMI - ECHEMI platform complaint penalty rules, Market Analysis - Monthly Report - July 2022- Hot Products, Price trends in the China's chemical market in the first half of 2022, Soybean Oil and Palm Oil Prices Bottom Out, The country's first "hydrolyzed zinc hyaluronate" was successfully filed, View all products of Market Price & Insight, Toxicity to daphnia and other aquatic invertebrates: no data available, Toxicity to microorganisms: no data available, ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road, RID: Regulation concerning the International Carriage of Dangerous Goods by Rail, IMDG: International Maritime Dangerous Goods, IATA: International Air Transportation Association, IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home, HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm, IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/, eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en, CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple, ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp, ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg, Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp, ECHA - European Chemicals Agency, website: https://echa.europa.eu/. 272 note). Consistent with FFDCA section 408(b)(2)(D), and the factors specified in FFDCA section 408(b)(2)(D), EPA has reviewed the available scientific data and other relevant information in support of this action. About the Federal Register Remove contact lenses, if present, after the first 5 minutes, then Prevent fire caused by electrostatic discharge steam. Bethany Benbow, Registration Division (7505P), Office of Pesticide Programs, Environmental Protection Agency, 1200 Pennsylvania Ave. How can I get electronic access to other related information? Section 408(b)(2)(A)(i) of FFDCA allows EPA to establish a tolerance (the legal limit for a pesticide chemical residue in or on a food) only if EPA Start Printed Page 70063determines that the tolerance is safe. Section 408(b)(2)(A)(ii) of FFDCA defines safe to mean that there is a reasonable certainty that no harm will result from aggregate exposure to the pesticide chemical residue, including all anticipated dietary exposures and all other exposures for which there is reliable information. This includes exposure through drinking water and in residential settings, but does not include occupational exposure. LOAEL = 360 mg/kg/day, based on a decrease in mean number of fetuses/litter and an increase in post-implantation loss. Palisade is a giberellic acid inhibitor and works primarily by reducing plant height. Health considerations Please store the product under the recommended conditions in the Certificate of Analysis. Dietary Exposure Evaluation Model (DEEMTM) 7.81 default concentration factors were used to estimate residues of trinexapac-ethyl in processed commodities. Neither comment was accompanied by any substantiation nor data supporting a conclusion that the tolerances being established in this action do not meet the FFDCA safety standard. MODDUS contains trinexapac-ethyl for use as a growth regulator in wheat, barley, oats, rye, triticale, durum wheat and ryegrass seed crops. Dietary exposure from food and feed uses. This feature is not available for this document. Chronic exposure. Further information about EPA's risk assessment and determination of safety can be found at http://www.regulations.gov in the document titled Trinexapac-ethyl. Well closed. Chemical Review Manager: Kelly Ballard (ballard.kelly@epa.gov), 703-305-8126. documents in the last year, 87 2. The President of the United States communicates information on holidays, commemorations, special observances, trade, and policy through Proclamations. This MRL is different than the tolerances established for trinexapac-ethyl in the United States. Palisade is a giberellic acid inhibitor and works primarily by reducing plant height. of the issuing agency. This repetition of headings to form internal navigation links publication in the future. Those assessments rely on tolerance-level residues, 2019 default processing factors, and an assumption of 100% crop treated (PCT). Because the acute and chronic dietary exposure estimates were based on several conservative assumptions (100% of crops treated with residues present at tolerance levels, default processing factors and screening level drinking water estimates), EPA is confident that the dietary exposure assessments do not underestimate risk to the general U.S. population and various population subgroups. Statutory and Executive Order Reviews, https://www.federalregister.gov/d/2012-4984, MODS: Government Publishing Office metadata, http://ecfr.gpoaccess.gov/cgi/t/text/text-idx?&c=ecfr&tpl=/ecfrbrowse/Title40/40tab_02.tpl, http://www.epa.gov/pesticides/factsheets/riskassess.htm, http://www.epa.gov/oppefed1/models/water/index.htm, http://www.epa.gov/pesticides/trac/science/trac6a05.pdf, http://www.epa.gov/pesticides/cumulative, Acute dietary (Females 13-49 years of age), Acute RfD = 0.6 mg/kg/day aPAD = 0.6 mg/kg/day. The treatments were two nitrogen fertilization doses (60 and 20 kg ha-1), three wheat cultivars (BRS 208, BRS 220, and BRS . There is the potential for incidental oral exposure; however, since there is no toxicological endpoint of concern for that route, a quantitative assessment was not conducted. Manganese and trinexapac-ethyl are compatible and seem to yield higher turf growth suppression than trinexapac-ethyl and iron. The article can be found at the link below: Anderson, N.P., D.P. Palisade did not affect lodging at Perkins in 2013. Quick Resources. for better understanding how a document is structured but has no substantive legal effect. Latest Registration Process: Registration Review . EPA is revising the tolerance expression to include the free and conjugated forms of the parent (trinexapac-ethyl) and acid. No. Refer for medical attention . Certain other material, such as copyrighted material, is not placed on the Internet and will be publicly available only in hard copy form. Trinexapac-ethyl is currently registered for the following uses that could result in residential exposures: Residential lawns, athletic fields, parks, and golf courses. In response among sites and years Agency understands the commenter 's concerns and recognizes that individuals! Variation in response among sites and years counts for this document for non-threshold risks, calculates. 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